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Comment
. 2015 Jun 15;21(12):2660-2.
doi: 10.1158/1078-0432.CCR-14-3190. Epub 2015 Apr 15.

CD38-Targeted Immunochemotherapy in Refractory Multiple Myeloma: A New Horizon

Jacob P Laubach  1 , Paul G Richardson  2
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Comment

CD38-Targeted Immunochemotherapy in Refractory Multiple Myeloma: A New Horizon

Jacob P Laubach et al. Clin Cancer Res. .

Abstract

CD38 is a type II transmembrane glycoprotein that is highly expressed in multiple myeloma and is a promising target for immunotherapy. Daratumumab is a human monoclonal antibody that has potent anti-multiple myeloma activity both as monotherapy and in combination with other multiple myeloma treatments, and has breakthrough designation on this basis.

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