Developing medicines that mimic the natural successes of the human genome: lessons from NPC1L1, HMGCR, PCSK9, APOC3, and CETP
- PMID: 25881938
- DOI: 10.1016/j.jacc.2015.02.049
Developing medicines that mimic the natural successes of the human genome: lessons from NPC1L1, HMGCR, PCSK9, APOC3, and CETP
Keywords: cholesterol; coronary disease; genetics; genetic association studies; human genome; medical; triglycerides.
Comment on
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Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: a 2 × 2 factorial Mendelian randomization study.J Am Coll Cardiol. 2015 Apr 21;65(15):1552-61. doi: 10.1016/j.jacc.2015.02.020. Epub 2015 Mar 11. J Am Coll Cardiol. 2015. PMID: 25770315 Free PMC article.
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