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. 2015 Feb;10(2):173-5.
doi: 10.4103/1673-5374.152359.

Hope on the (fruit) fly: the Drosophila wing paradigm of axon injury

Yanshan Fang  1 , Nancy M Bonini  2
Affiliations

Hope on the (fruit) fly: the Drosophila wing paradigm of axon injury

Yanshan Fang et al. Neural Regen Res. 2015 Feb.
No abstract available

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Figures

Figure 1
Figure 1
The adult Drosophila wing nerve and its CNS projections. (A) A dissected thoracic ganglion showing the wing nerve projection labeled by mCD8-GFP, using the dpr-GAL4 driver which highlights a subset of the sensory neurons (Fang et al., 2012, 2013). Only one wing projection is present in the image (solid arrows); the projection of the other wing is absent (open arrows) due to injury-induced axon degeneration. Scale bar: 50 μm. (B) An illustration of the peripheral nervous system in the Drosophila wing. The nerve projections (schematically illustrated in green) can be directly visualized when highlighted with fluorescent protein markers such as GFP and RFP. The wing nerve is comprised of the ~225 axons of the sensory neurons (positions of the neural cells bodies schematically illustrated in red) in the L1 vein, the coastal vein and the L3 vein. CNS: central nervous system; GFP: Green fluorescent protein; RFP: red fluorescent protein.
See this image and copyright information in PMC

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