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. 2015 Sep;30(9):1618-22.
doi: 10.1016/j.arth.2015.04.005. Epub 2015 Apr 8.

Risk Factors for Recurrence of Periprosthetic Knee Infection

Vasileios I Sakellariou  1 , Lazaros A Poultsides  1 , Theofanis Vasilakakos  1 , Peter Sculco  1 , Yan Ma  1 , Thomas P Sculco  1
Affiliations

Risk Factors for Recurrence of Periprosthetic Knee Infection

Vasileios I Sakellariou et al. J Arthroplasty. 2015 Sep.

Abstract

We retrospectively reviewed 110 patients who underwent two-stage revision surgery in order to identify potential risk factors for recurrence of periprosthetic infection. We found that patients with inflammatory arthritis (P=0.0125), perioperative hematoma formation (P=0.0422), wound dehiscence (P=0.042), and those who are chronic Staphylococcus carriers (P=0.0177) were associated with an increased incidence of re-infection. The duration of intravenous antibiotic therapy less than 6 weeks was associated with a reduced risk of reinfection to greater than 6 weeks (P=0.03). Multivariate analysis indicated that wound dehiscence (odds ratio [OR], 5.119; 95% confidence interval [CI], 1.367-19.17), and Staphylococcus carriers (OR, 11.419; 95% CI, 1.376-94.727) are significant predictors of recurrence (P=0.0153 and 0.0241, respectively).

Keywords: infection; knee; periprosthetic; recurrence; two-stage.

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