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. 2015 Oct;9(2):347-50.
doi: 10.1007/s12104-015-9607-1. Epub 2015 Apr 19.

Backbone and side-chain (1)H, (15)N, (13)C assignment and secondary structure of BPSL1445 from Burkholderia pseudomallei

Giacomo Quilici  1 , Andrea Berardi  1 , Davide Gaudesi  1 , Louise J Gourlay  2 , Martino Bolognesi  2 , Giovanna Musco  3
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Backbone and side-chain (1)H, (15)N, (13)C assignment and secondary structure of BPSL1445 from Burkholderia pseudomallei

Giacomo Quilici et al. Biomol NMR Assign. 2015 Oct.

Abstract

BPSL1445 is a lipoprotein produced by the Gram-negative bacterium Burkholderia pseudomallei (B. pseudomallei), the etiological agent of melioidosis. Immunodetection assays against sera patients using protein microarray suggest BPSL1445 involvement in melioidosis. Herein we report backbone, side chain NMR assignment and secondary structure for the recombinant protein.

Keywords: Biological warfare agent; Host-pathogen interactions; Infectious diseases; Melioidosis; Vaccine.

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