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Comparative Study
. 2015 Apr 20;4(4):e001777.
doi: 10.1161/JAHA.115.001777.

Right ventricular outflow tract septal pacing is superior to right ventricular apical pacing

Cao Zou  1 , Jianping Song  1 , Hui Li  1 , Xingmei Huang  2 , Yuping Liu  2 , Caiming Zhao  3 , Xin Shi  3 , Xiangjun Yang  1
Affiliations
Comparative Study

Right ventricular outflow tract septal pacing is superior to right ventricular apical pacing

Cao Zou et al. J Am Heart Assoc. .

Abstract

Background: The effects of right ventricular apical pacing (RVAP) and right ventricular outflow tract (RVOT) septal pacing on atrial and ventricular electrophysiology have not been thoroughly compared.

Methods and results: To identify a more favorable pacing strategy with fewer adverse effects, 80 patients who had complete atrioventricular block with normal cardiac function and who were treated with either RVAP (n=42) or RVOT septal pacing (n=38) were recruited after an average of 2 years of follow-up. The data from electrocardiography and echocardiography performed before pacemaker implantation and at the end of follow-up were collected. The patients in the RVOT septal pacing and RVAP groups showed similar demographic and clinical characteristics before pacing treatments. After a mean follow-up of 2 years, the final maximum P-wave duration; P-wave dispersion; Q-, R-, and S-wave complex duration; left atrial volume index; left ventricular end-systolic diameter; ratio of transmitral early diastolic filling velocity to mitral annular early diastolic velocity; and interventricular mechanical delay in the RVOT septal pacing group were significantly less than those in the RVAP group (P<0.05). The final left ventricular ejection fraction of the RVOT septal pacing group was significantly higher than that of the RVAP group (P<0.05).

Conclusions: Compared with RVAP, RVOT septal pacing has fewer adverse effects regarding atrial electrical activity and structure in patients with normal cardiac function.

Keywords: cardiovascular diseases; electrophysiology; pacemaker.

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Figures

Figure 1.
Figure 1.
Exemplificative diagram for RVOT septal and RVAP pacing. Chest x‐ray showing the position of the right ventricular lead at the right ventricular outflow tract septum in right anterior oblique (30°) (A) and left anterior oblique (45°) (B) views. Twelve‐lead electrocardiograms indicating the site of RVOT septal pacing (C) and RVAP (D). RVAP indicates right ventricular apical pacing; RVOT, right ventricular outflow tract.
See this image and copyright information in PMC

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