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. 2015 May;21(5):872-4.
doi: 10.3201/eid2105.141839.

Full-Genome Sequence of Influenza A(H5N8) Virus in Poultry Linked to Sequences of Strains from Asia, the Netherlands, 2014

Ruth Bouwstra, Rene Heutink, Alex Bossers, Frank Harders, Guus Koch, Armin Elbers

Full-Genome Sequence of Influenza A(H5N8) Virus in Poultry Linked to Sequences of Strains from Asia, the Netherlands, 2014

Ruth Bouwstra et al. Emerg Infect Dis. 2015 May.

Abstract

Genetic analyses of highly pathogenic avian influenza A(H5N8) virus from the Netherlands, and comparison with strains from Europe, South Korea, and Japan, showed a close relation. Data suggest the strains were probably carried to the Netherlands by migratory wild birds from Asia, possibly through overlapping flyways and common breeding sites in Siberia.

Keywords: Asian strains; H5N8; genome sequencing; influenza; poultry; the Netherlands; viruses.

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Figures

Figure
Figure
Phylogenetic tree of hemagglutinin gene of highly pathogenic avian influenza A(H5N8) viruses. The evolutionary history was inferred by using the maximum-likelihood method based on the Tamura-Nei model in MEGA6 (14). The tree with the highest log likelihood is shown. The percentage of trees in which the associated taxa clustered together is shown next to the branches. Initial tree(s) for the heuristic search were obtained automatically by applying neighbor-joining and BIONJ (15) algorithms to a matrix of pairwise distances estimated by using the maximum composite likelihood approach and then selecting the topology with superior log likelihood value. The Tamura-Nei model was used by assuming a gamma distributed rate among nucleotide sites. The tree is drawn to scale; scale bar indicates the number of nucleotide substitutions per site. The analysis involved 25 nt sequences. All positions containing gaps and missing data were eliminated. There were a total of 761 nt positions in the final dataset. Black dot indicates A/chicken/Netherlands/14015526/2014; black square indicates A/wigeon/Sakha/1/2014.
See this image and copyright information in PMC

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