Zero tolerance: amphipathic helices in endocytosis
- PMID: 25898162
- DOI: 10.1016/j.devcel.2015.04.007
Zero tolerance: amphipathic helices in endocytosis
Abstract
Endocytosis is the physical battle to form a new vesicle in the face of counteracting forces, such as membrane tension. Skruzny et al. (2015) and Miller et al. (2015) now shed light on endocytic proteins that bear a "Helix 0" and on the proteins' role in the struggle to make clathrin-coated vesicles.
Copyright © 2015 Elsevier Inc. All rights reserved.
Comment on
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An organized co-assembly of clathrin adaptors is essential for endocytosis.Dev Cell. 2015 Apr 20;33(2):150-62. doi: 10.1016/j.devcel.2015.02.023. Dev Cell. 2015. PMID: 25898165
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CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature.Dev Cell. 2015 Apr 20;33(2):163-75. doi: 10.1016/j.devcel.2015.03.002. Dev Cell. 2015. PMID: 25898166 Free PMC article.
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