BORC and BLOC-1: Shared subunits in trafficking complexes
- PMID: 25898163
- DOI: 10.1016/j.devcel.2015.04.008
BORC and BLOC-1: Shared subunits in trafficking complexes
Abstract
Intracellular trafficking requires careful positioning of organelles within the cellular three-dimensional space. Pu et al. (2015) now provide evidence for a multisubunit complex, named BORC, that regulates the positioning of lysosomes at the cell periphery and consequently affects cell migration.
Copyright © 2015 Elsevier Inc. All rights reserved.
Comment on
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BORC, a multisubunit complex that regulates lysosome positioning.Dev Cell. 2015 Apr 20;33(2):176-88. doi: 10.1016/j.devcel.2015.02.011. Dev Cell. 2015. PMID: 25898167 Free PMC article.
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