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. 2015:11:11-17.
doi: 10.1016/j.ijscr.2015.03.010. Epub 2015 Apr 4.

Rare breast malignancies and review of literature: A single centres experience

Cho Ee Ng  1 , Nithia Angamuthu  2 , Tarannum Fasih  3
Affiliations

Rare breast malignancies and review of literature: A single centres experience

Cho Ee Ng et al. Int J Surg Case Rep. 2015.

Abstract

Introduction: Breast cancer is a heterogeneous condition, with variants which are less common but still very well defined by the World Health Organization (WHO) classification. With the small number of cases each year large trials are difficult to perform. This series aims to discuss the rare breast malignancies encountered within a breast department and the evidence based approached to their management.

Method: Literature search of electronic databases via PubMed and the search engines Google/Google Scholar were used. Emphasis on keywords: breast cancer and the type of histology used to limit search. Searches were screened and those articles suitable had full text versions retrieved. The references to all retrieved texts were searched for further relevant studies.

Conclusion: Due to the rarity of some of these breast cancers, systematic evaluation of patient with detailed histopathology will aid accurate diagnosis and management. The series hopes to add the existing understanding of this small percentage of cases.

Keywords: Adenoid cystic carcinoma; Lymphoma; Metaplastics carcinoma; Metastatic ovarian cancer; Osteosarcoma; Rare breast malignancies.

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Figures

Fig. 1
Fig. 1
Immunohistochemistry sample of lymphoma of breast.
Fig. 2
Fig. 2
Immunohistochemistry of metastatic poorly differentiated serous papillary carcinoma.
Fig. 3
Fig. 3
Staining of WT1 for CA 125.
Fig. 4
Fig. 4
Slide rich with osteoid multinucleate giant cells and abundant undifferentiated stroma which is positive for vimentin.
Fig. 5
Fig. 5
Staining for CK epithelial marker.
Fig. 6
Fig. 6
Staining for E cadherin.
Fig. 7
Fig. 7
Histology demonstrating squamous cell carcinoma of the breast.
Fig. 8
Fig. 8
Specimen demonstrating glandular lumens with eosinophilic material.
See this image and copyright information in PMC

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