Treatment of experimental disseminated candidiasis with cilofungin
- PMID: 2589848
- PMCID: PMC172760
- DOI: 10.1128/AAC.33.10.1811
Treatment of experimental disseminated candidiasis with cilofungin
Abstract
The efficacy of cilofungin treatment of experimental disseminated candidiasis in rabbits was examined. Cilofungin treatment reduced yeast counts, especially in the kidney, with activity comparable to that of amphotericin B. The peak level of cilofungin in serum was measured at 5 min after administration of a single dose, with no drug detectable after 90 min.
Similar articles
-
Efficacy of cilofungin therapy administered by continuous intravenous infusion for experimental disseminated candidiasis in rabbits.Antimicrob Agents Chemother. 1992 Jan;36(1):56-8. doi: 10.1128/AAC.36.1.56. Antimicrob Agents Chemother. 1992. PMID: 1590700 Free PMC article.
-
Comparison of cilofungin and amphotericin B for therapy of murine candidiasis.Antimicrob Agents Chemother. 1990 Aug;34(8):1619-21. doi: 10.1128/AAC.34.8.1619. Antimicrob Agents Chemother. 1990. PMID: 2221875 Free PMC article.
-
Treatment of murine invasive candidiasis with amphotericin B and cilofungin: evidence for enhanced activity with combination therapy.Antimicrob Agents Chemother. 1991 Oct;35(10):2128-30. doi: 10.1128/AAC.35.10.2128. Antimicrob Agents Chemother. 1991. PMID: 1759836 Free PMC article.
-
Caspofungin: a review of its use in oesophageal candidiasis, invasive candidiasis and invasive aspergillosis.Drugs. 2003;63(20):2235-63. doi: 10.2165/00003495-200363200-00008. Drugs. 2003. PMID: 14498760 Review.
-
Antifungals in systemic neonatal candidiasis.Drugs. 2004;64(9):949-68. doi: 10.2165/00003495-200464090-00003. Drugs. 2004. PMID: 15101785 Review.
Cited by
-
Efficacy of cilofungin therapy administered by continuous intravenous infusion for experimental disseminated candidiasis in rabbits.Antimicrob Agents Chemother. 1992 Jan;36(1):56-8. doi: 10.1128/AAC.36.1.56. Antimicrob Agents Chemother. 1992. PMID: 1590700 Free PMC article.
-
Antifungal effects of the nonlinear pharmacokinetics of cilofungin, a 1,3-beta-glucan synthetase inhibitor, during continuous and intermittent intravenous infusions in treatment of experimental disseminated candidiasis.Antimicrob Agents Chemother. 1991 Jul;35(7):1321-8. doi: 10.1128/AAC.35.7.1321. Antimicrob Agents Chemother. 1991. PMID: 1929288 Free PMC article.
-
Comparison of cilofungin and amphotericin B for therapy of murine candidiasis.Antimicrob Agents Chemother. 1990 Aug;34(8):1619-21. doi: 10.1128/AAC.34.8.1619. Antimicrob Agents Chemother. 1990. PMID: 2221875 Free PMC article.
-
Comparison of the efficacy of cilofungin, fluconazole and amphotericin B in the treatment of systemic Candida albicans infection in the neutropenic mouse.Infection. 1992 May-Jun;20(3):168-70. doi: 10.1007/BF01704614. Infection. 1992. PMID: 1644494
-
Compounds active against cell walls of medically important fungi.Clin Microbiol Rev. 1993 Jan;6(1):1-21. doi: 10.1128/CMR.6.1.1. Clin Microbiol Rev. 1993. PMID: 8457977 Free PMC article. Review.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical