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. 1989 Oct;38(10):1136-41.

[In vitro detection of ovalbumin-specific IgA producing cells from lymphocytes of patients with hen-egg allergy]

[Article in Japanese]
K Yamaguchi, T Noma, M Baba, J Yata
  • PMID: 2589970

[In vitro detection of ovalbumin-specific IgA producing cells from lymphocytes of patients with hen-egg allergy]

[Article in Japanese]
K Yamaguchi et al. Arerugi. 1989 Oct.

Abstract

We studied antigen-specific IgA production from the peripheral lymphocytes of children with hen-egg allergy by using the method of indirect plaque forming cell (PFC) assay. The number of OVA-specific IgA-PFC generated from the patient lymphocytes was low (6 +/- 3/7 X 10(4) non T cells) in comparison with age-matched normal children (112 +/- 18/7 X 10(4) non T cells). The numbers of OVA-specific IgG-PFC and IgM-PFC generated from the patient lymphocytes were not so different from those of the age-matched normal children. This indicates that the activity of OVA-specific IgA-antibody production was reduced in patients with hen-egg allergy.

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