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. 2015 Jul;53(7):2332-6.
doi: 10.1128/JCM.00123-15. Epub 2015 Apr 22.

Molecular Basis of Resistance to Selected Antimicrobial Agents in the Emerging Zoonotic Pathogen Streptococcus suis

Mamata Gurung  1 , Migma Dorji Tamang  1 , Dong Chan Moon  1 , Su-Ran Kim  1 , Jin-Ha Jeong  1 , Geum-Chan Jang  1 , Suk-Chan Jung  1 , Yong-Ho Park  2 , Suk-Kyung Lim  3
Affiliations

Molecular Basis of Resistance to Selected Antimicrobial Agents in the Emerging Zoonotic Pathogen Streptococcus suis

Mamata Gurung et al. J Clin Microbiol. 2015 Jul.

Abstract

Characterization of 227 Streptococcus suis strains isolated from pigs during 2010 to 2013 showed high levels of resistance to clindamycin (95.6%), tilmicosin (94.7%), tylosin (93.8%), oxytetracycline (89.4%), chlortetracycline (86.8%), tiamulin (72.7%), neomycin (70.0%), enrofloxacin (56.4%), penicillin (56.4%), ceftiofur (55.9%), and gentamicin (55.1%). Resistance to tetracyclines, macrolides, aminoglycosides, and fluoroquinolone was attributed to the tet gene, erm(B), erm(C), mph(C), and mef(A) and/or mef(E) genes, aph(3')-IIIa and aac(6')-Ie-aph(2″)-Ia genes, and single point mutations in the quinolone resistance-determining region of ParC and GyrA, respectively.

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References

    1. Lun ZR, Wang QP, Chen XG, Li AX, Zhu XQ. 2007. Streptococcus suis: an emerging zoonotic pathogen. Lancet Infect Dis 7:201–209. doi:10.1016/S1473-3099(07)70001-4. - DOI - PubMed
    1. Gottschalk M, Segura M, Xu J. 2007. Streptococcus suis infections in humans: the Chinese experience and the situation in North America. Anim Health Res Rev 8:29–45. doi:10.1017/S1466252307001247. - DOI - PubMed
    1. Feng Y, Zhang H, Wu Z, Wang S, Cao M, Hu D, Wang C. 2014. Streptococcus suis infection: an emerging/reemerging challenge of bacterial infectious diseases? Virulence 5:477–497. doi:10.4161/viru.28595. - DOI - PMC - PubMed
    1. Yu H, Jing H, Chen Z, Zheng H, Zhu X, Wang H, Wang S, Liu L, Zu R, Luo L, Xiang N, Liu H, Liu X, Shu Y, Lee SS, Chuang SK, Wang Y, Xu J, Yang W. 2006. Human Streptococcus suis outbreak, Sichuan, China. Emerg Infect Dis 12:914–920. doi:10.3201/eid1206.051194. - DOI - PMC - PubMed
    1. Perch B, Kristjansen P, Skadhauge K. 1968. Group R streptococci pathogenic for man: two cases of meningitis and one fatal case of sepsis. Acta Pathol Microbiol Scand 74:69–76. - PubMed

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