Editor's Choice-Chest pain relief in patients with acute myocardial infarction
- PMID: 25904757
- DOI: 10.1177/2048872615584078
Editor's Choice-Chest pain relief in patients with acute myocardial infarction
Abstract
Chest pain is the prevalent symptom at presentation in patients with acute myocardial infarction (AMI). Despite the complete absence of rigorous studies designed to assess the impact of morphine administration in patients with AMI, clinical practice guidelines strongly recommend morphine for analgesia. However, when using morphine to relieve chest pain in AMI patients, physicians must be aware that hypotension, respiratory depression, vomiting, and delayed onset of action of antiplatelet agents are potential unwanted side effects of the drug. The purpose of this report is to review morphine's clinical and side effects and to propose strategies able to reduce chest pain in AMI patients.
Keywords: STEMI; antiplatelets; chest pain; morphine; myocardial infarction; prasugrel; ticagrelor.
© The European Society of Cardiology 2015.
Similar articles
-
Treatment of pain in acute myocardial infarction.Br Heart J. 1989 Jan;61(1):9-13. doi: 10.1136/hrt.61.1.9. Br Heart J. 1989. PMID: 2563657 Free PMC article. Review.
-
Acute myocardial infarction patients' chest pain as monitored and evaluated by ambulance personnel.Intensive Crit Care Nurs. 1992 Jun;8(2):113-7. doi: 10.1016/0964-3397(92)90040-q. Intensive Crit Care Nurs. 1992. PMID: 1611285
-
Analgesia for acute myocardial infarction pain.Ann Emerg Med. 2003 May;41(5):753-4. doi: 10.1067/mem.2003.165. Ann Emerg Med. 2003. PMID: 12744246 No abstract available.
-
Morphine in the setting of acute myocardial infarction: pros and cons.Am J Emerg Med. 2016 Apr;34(4):746-8. doi: 10.1016/j.ajem.2016.01.016. Epub 2016 Jan 21. Am J Emerg Med. 2016. PMID: 26874396 No abstract available.
-
Beyond Traditional Pain Relief: A Review of Alternative Analgesics in Myocardial Infarction Patient Management.J Pain Palliat Care Pharmacother. 2024 Jun;38(2):157-169. doi: 10.1080/15360288.2024.2304008. Epub 2024 Feb 8. J Pain Palliat Care Pharmacother. 2024. PMID: 38329476 Review.
Cited by
-
Nitrous oxide/oxygen plus acetaminophen versus morphine in ST elevation myocardial infarction: open-label, cluster-randomized, non-inferiority study.Scand J Trauma Resusc Emerg Med. 2020 May 12;28(1):36. doi: 10.1186/s13049-020-00731-y. Scand J Trauma Resusc Emerg Med. 2020. PMID: 32398160 Free PMC article. Clinical Trial.
-
δ-Opioid Receptor as a Molecular Target for Increasing Cardiac Resistance to Reperfusion in Drug Development.Biomedicines. 2023 Jul 3;11(7):1887. doi: 10.3390/biomedicines11071887. Biomedicines. 2023. PMID: 37509526 Free PMC article. Review.
-
A Review of Adverse Outcomes Following Intravenous Morphine Usage for Pain Relief in Acute Coronary Syndrome.Cureus. 2018 Sep 4;10(9):e3246. doi: 10.7759/cureus.3246. Cureus. 2018. PMID: 30937227 Free PMC article. Review.
-
Morphine delays and attenuates ticagrelor exposure and action in patients with myocardial infarction: the randomized, double-blind, placebo-controlled IMPRESSION trial.Eur Heart J. 2016 Jan 14;37(3):245-52. doi: 10.1093/eurheartj/ehv547. Epub 2015 Oct 21. Eur Heart J. 2016. PMID: 26491112 Free PMC article. Clinical Trial.
-
Pre-hospital treatment of patients with acute coronary syndrome: Recommendations for medical emergency teams. Expert position update 2022.Cardiol J. 2022;29(4):540-552. doi: 10.5603/CJ.a2022.0026. Epub 2022 May 6. Cardiol J. 2022. PMID: 35514089 Free PMC article. No abstract available.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
