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Review

Calcium and Phosphate Homeostasis

In: Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000.
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Review

Calcium and Phosphate Homeostasis

Joseph L. Shaker et al.
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Excerpt

Calcium and phosphate are critical to human physiology (e.g., neuromuscular function) and are also needed for skeletal mineralization. An understanding of calcium and phosphate metabolism is required for the clinician to evaluate disorders of the levels of calcium and phosphorus as well as metabolic skeletal disorders. In this chapter, we review calcium and phosphate homeostasis including the critical organs involved (skeleton, parathyroids, GI tract, kidneys etc.) as well as the hormones (PTH, vitamin D, FGF23, calcitonin) that regulate calcium and phosphate. For complete coverage of all related areas of Endocrinology, please visit our on-line FREE web-text, WWW.ENDOTEXT.ORG.

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References

    1. Deftos, LJ: Clinical Essentials of Calcium and Skeletal Metabolism, Professional Communication Inc, First Edition, pp. 1-208, 1998 (Published on-line at Medscape.com).
    1. Brown EM: Physiology of Calcium Homeostasis. In: The Parathyroids, Second Editon, JP Bilezikian, R Marcus, and A Levine (eds.); Chapter 10, pp. 167-182, 2001.
    1. Bruder JM, Guise TA, and Mundy GR: Mineral Metabolism. In: Endocrinology & Metabolism, Fourth Edition, P. Felig and LA Frohman (eds.); Chapter 22, pp.10791159, 2001.
    1. Drezner, MK: Phosphorus Homeostasis and Related Disorders. In: Principles of Bone Biology, Second Edition, JP Bilezikian, LG Raisz, and GA Rodan (eds.); Chapter 22, pp.321-338, 2002.
    1. Yanagawa N and Lee DBN: Renal Handling of Calcium and Phosphorus. In: Disorders of Bone and Mineral Metabolism, FL Coe and MJ Favus (eds.); Chapter 1, pp.3-40, 1992.

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