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Review
. 2015 Jun;11(6):691-3.
doi: 10.1586/1744666X.2015.1039514. Epub 2015 Apr 23.

Treating to target in axial spondyloarthritis: defining the target and the arrow

Daniel Wendling  1
Affiliations
Review

Treating to target in axial spondyloarthritis: defining the target and the arrow

Daniel Wendling. Expert Rev Clin Immunol. 2015 Jun.

Abstract

The treat-to-target concept is currently proposed in axial spondyloarthritis and aims for remission to be reached and maintained. Consensual definitions of remission and flare of the disease are currently lacking but are needed to validate this strategy and to confirm the window of opportunity hypothesis. The discovery of new therapeutic targets, such as IL-23 and IL-17, will enable and enlarge the possibility of targeted therapies in axial spondyloarthritis.

Keywords: IL 17; IL 23; ankylosing spondylitis; remission; spondyloarthritis; treatment.

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