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Review
. 2015 Mar-Apr;41(2):191-5.
doi: 10.1590/S1806-37132015000004412. Epub 2015 Apr 18.

Lymphadenopathy and fever in a chef during a stay in Europe

[Article in English, Portuguese]
Letícia Kawano-Dourado  1 , Daniel Antunes Silva Peirera  1 , Alexandre de Melo Kawassaki  1 , Marisa Dolhnikoff  2 , Marcos Vinicius da Silva  3 , Ronaldo Adib Kairalla  4
Affiliations
Review

Lymphadenopathy and fever in a chef during a stay in Europe

[Article in English, Portuguese]
Letícia Kawano-Dourado et al. J Bras Pneumol. 2015 Mar-Apr.

Abstract

This case illustrates a rare presentation (as lymphadenopathy and fever) of one of the most common zoonotic diseases worldwide--brucellosis--in a 22-year-old Brazilian male (a chef) who had recently returned to Brazil after having lived in and traveled around Europe for one year. The histopathology, clinical history, and response to treatment were all consistent with a diagnosis of brucellosis, which was confirmed by PCR in a urine sample. We also review some aspects of brucellosis, such as the clinical features, diagnosis, and management.

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Figures

Figure 1 -
Figure 1 -. (A) Chest X-ray, posteroanterior view, showing a widened paratracheal stripe (arrow). (B) Highresolution CT of the chest revealing enlarged mediastinal lymph nodes (arrow).
Figure 2 -
Figure 2 -. Photomicrographs of a cervical lymph node biopsy sample. Lymphoid tissue is replaced by necrotizing granulomatous inflammation (panel A). Note palisading epithelioid cells (panel B, arrows), extensive neutrophil-rich suppurative necrosis (panel C, letter N), and scattered giant cells (panel D, arrows). Hematoxylin-eosin staining (magnification varies; see the scale bars displayed in the panels).
See this image and copyright information in PMC

References

    1. El-Zammar OA, Katzenstein AL. Pathological diagnosis of granulomatous lung disease: a review. Histopathology. 2007;50(3):289–310. http://dx.doi.org/10.1111/j.1365-2559.2006.02546.x - DOI - PubMed
    1. Bosilkovski M, Krteva L, Dimzova M, Vidinic I, Sopova Z, Spasovska K. Human brucellosis in Macedonia - 10 years of clinical experience in endemic region. Croat Med J. 2010;51(4):327–336. http://dx.doi.org/10.3325/cmj.2010.51.327 - DOI - PMC - PubMed
    1. Pappas G, Papadimitriou P, Akritidis N, Christou L, Tsianos EV. The new global map of human brucellosis. Lancet Infect Dis. 2006;6(2):91–99. http://dx.doi.org/10.1016/S1473-3099(06)70382-6 - DOI - PubMed
    1. Franco MP, Mulder M, Gilman RH, Smits HL. Human brucellosis. Lancet Infect Dis. 2007;7(12):775–786. http://dx.doi.org/10.1016/S1473-3099(07)70286-4 - DOI - PubMed
    1. Memish Z, Mah MW, Al Mahmoud S, Al Shaalan M, Khan MY. Brucella bacteraemia: clinical and laboratory observations in 160 patients. J Infect. 2000;40(1):59–63. http://dx.doi.org/10.1053/jinf.1999.0586 - DOI - PubMed