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Comment
. 2015 Apr 23;161(3):431-432.
doi: 10.1016/j.cell.2015.04.009.

Gradients are shaping up

Tobias Bollenbach  1 , Carl-Philipp Heisenberg  2
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Free article
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Gradients are shaping up

Tobias Bollenbach et al. Cell. .
Free article

Abstract

In animal embryos, morphogen gradients determine tissue patterning and morphogenesis. Shyer et al. provide evidence that, during vertebrate gut formation, tissue folding generates graded activity of signals required for subsequent steps of gut growth and differentiation, thereby revealing an intriguing link between tissue morphogenesis and morphogen gradient formation.

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