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. 2015 Jun 19;33 Suppl 3(Suppl 3):C1-2.
doi: 10.1016/j.vaccine.2015.04.033. Epub 2015 Apr 21.

Building the case for wider use of typhoid vaccines

John A Crump  1
Affiliations

Building the case for wider use of typhoid vaccines

John A Crump. Vaccine. .

Abstract

Efficacious typhoid fever vaccines have been available for decades. Typhoid fever burden of disease estimates indicate a substantial burden of illness and death in low-resource areas. The World Health Organization has recommended that countries consider the use of typhoid vaccines for high-risk groups and populations, and for outbreak control. Despite this, typhoid vaccines are not widely used in endemic areas. By examining strategies to improve burden of disease data, use of transmission dynamic models, economic evaluations, vaccine strategies, and experiences with typhoid vaccine pilot projects, the papers in this supplement help to plot the path toward rational and wider use of typhoid vaccines.

Keywords: Developing countries; Typhoid fever; Vaccines.

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Conflict of interest statement

Conflicts of interest statement: JAC serves as a Resource Advisor, Invasive Salmonella infections, World Health Organization Foodborne Diseases Burden Epidemiology Reference Group; an Expert, Institute for Health Metrics and Evaluation, Global Burden of Disease 2013 project; and a Reviewer, Coalition against Typhoid (CaT) typhoid vaccine investment case.

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