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Comment
. 2015 Jun;23(6):330-1.
doi: 10.1016/j.tim.2015.04.003. Epub 2015 Apr 23.

Novel role of DNA in neutrophil extracellular traps

Christoph Georg Baums  1 , Maren von Köckritz-Blickwede  2
Affiliations
Comment

Novel role of DNA in neutrophil extracellular traps

Christoph Georg Baums et al. Trends Microbiol. 2015 Jun.

Abstract

Neutrophil extracellular traps (NETs) have been shown to play a crucial role in health and disease. In a recent paper in PLoS Pathogens, Halverson et al. demonstrate that the DNA backbone of NETs contributes to its antibacterial activity and serves as signal for entrapped microbes to employ immune evasion strategies.

Keywords: DNA; Pseudomonas aeruginosa; Staphylococcus aureus; antimicrobial activity; neutrophils.

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