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. 2015 Apr 16;20(4):6970-7.
doi: 10.3390/molecules20046970.

Alkylamides of Acmella oleracea

Yuan-Bin Cheng  1   2 , Rosa Huang Liu  3 , Meng-Chi Ho  4 , Tung-Ying Wu  5   6 , Ching-Yeu Chen  7 , I-Wen Lo  8 , Ming-Feng Hou  9 , Shyng-Shiou Yuan  10 , Yang-Chang Wu  11   12   13   14 , Fang-Rong Chang  15   16   17   18
Affiliations

Alkylamides of Acmella oleracea

Yuan-Bin Cheng et al. Molecules. .

Abstract

Phytochemical investigation of the flowers of Acmella oleracea had resulted in the isolation of one new alkylamide, (2E,5Z)-N-isobutylundeca-2,5-diene-8,10-diynamide (1), together with four known analogues (2-5). The structures of these compounds were determined by the interpretation of spectroscopic methods, especially NMR technologies (COSY, HSQC, HMBC, and NOESY). In addition, a convenient method for concentrating the alkylamide-rich fraction and analyzing fingerprint profile of A. oleracea was established.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Scheme 1
Scheme 1
The structures of alkylamides 1−5.
Figure 1
Figure 1
Selected COSY (bold line) and HMBC (arrow) correlations of 1.
Figure 2
Figure 2
Qualitative HPLC profile of the crude extract of A. oleracea flowers shown the major compounds 4 and 5.
See this image and copyright information in PMC

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