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Review
. 2015 May;35(5):384-6.
doi: 10.1038/jp.2015.10.

Congenital chylothorax treated with oral sildenafil: a case report and review of the literature

D T Malleske  1 , B A Yoder  1
Affiliations
Review

Congenital chylothorax treated with oral sildenafil: a case report and review of the literature

D T Malleske et al. J Perinatol. 2015 May.

Abstract

Congenital chylothorax (CC) can result from a congenital malformation or an acquired obstruction or disruption of the thoracic duct. Recently, oral administration of the phosphodiesterase-5 inhibitor, sildenafil, was reported to be effective in resolving non-pulmonary lymphatic malformations in infants and young children. We report a case of CC in a late preterm infant with congenital pulmonary lymphangiectasia where octreotide was not effective, but management with oral sildenafil was successful.

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