Case Reports
doi: 10.4269/ajtmh.15-0077.
Epub 2015 Apr 27.
Failure of ivermectin per rectum to achieve clinically meaningful serum levels in two cases of Strongyloides hyperinfection
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- PMID: 25918215
- PMCID: PMC4497912
- DOI: 10.4269/ajtmh.15-0077
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Case Reports
Failure of ivermectin per rectum to achieve clinically meaningful serum levels in two cases of Strongyloides hyperinfection
Am J Trop Med Hyg.
2015 Jul.
Abstract
Two cases of Strongyloides hyperinfection are presented. Ivermectin was initially administered orally and per rectum pending the availability of subcutaneous (SC) preparations. In neither case did rectal suppositories of ivermectin achieve clinically meaningful serum values. Clinicians should use SC preparations of ivermectin as early as possible in Strongyloides hyperinfection and dissemination.
© The American Society of Tropical Medicine and Hygiene.
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