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. 2015 Apr 27;209(2):189.
doi: 10.1083/jcb.2092fta.

Demystifying Aurora B

Demystifying Aurora B

Caitlin Sedwick. J Cell Biol. .

Abstract

In 2003, two papers uncovered the mitotic functions of Aurora B using novel small molecule inhibitors.

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Figures

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Compared with control cells (left), inhibition of Aurora B (right) causes impaired alignment of chromosomes (blue) on the mitotic spindle (green) at metaphase. ADAPTED FROM DITCHFIELD ET AL., 2003

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