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Review
. 2016 Feb;1366(1):40-8.
doi: 10.1111/nyas.12765. Epub 2015 Apr 28.

Imaging of cerebrovascular disorders: precision medicine and the collaterome

David S Liebeskind  1 , Edward Feldmann  2
Affiliations
Review

Imaging of cerebrovascular disorders: precision medicine and the collaterome

David S Liebeskind et al. Ann N Y Acad Sci. 2016 Feb.

Abstract

Imaging of stroke and neurovascular disorders has profoundly enhanced clinical practice and related research during the last 40 years since the introduction of computed tomography (CT) and magnetic resonance imaging (MRI) enabled mapping of the brain. We highlight recent advances in neurovascular imaging. We describe how the convergence of readily available data and new clinical trial paradigms will recast our methods for studying the neurovascular patient. The application of a precision medicine approach to the collaterome, a comprehensive synthesis of neurovascular pathophysiology, will entail novel methods for clinical trial randomization, collection of routine and clinical trial imaging results, data archiving, and analysis.

Keywords: collaterals; data science; imaging; stroke.

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Conflict of interest statement

Conflicts of interest

D. L. is a scientific consultant regarding trial design and conduct to Stryker (modest) and Covidien (modest). He was employed by the University of California, which holds a patent on retriever devices for stroke, at the time of this work.

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