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. 2015 Jul;25(7):1263-70.
doi: 10.1007/s11695-015-1666-y.

The Short-Term Remission of Diabetic Nephropathy After Roux-en-Y Gastric Bypass in Chinese Patients of T2DM with Obesity

Hongwei Zhang  1 , Jianzhong Di, Haoyong Yu, Xiaodong Han, Kun Li, Pin Zhang
Affiliations

The Short-Term Remission of Diabetic Nephropathy After Roux-en-Y Gastric Bypass in Chinese Patients of T2DM with Obesity

Hongwei Zhang et al. Obes Surg. 2015 Jul.

Abstract

The study aimed to examine the effect of gastric bypass on diabetic nephropathy (DN) in Chinese patients. A retrospective study of 101 samples with DN stages I to IV underwent Roux-en-Y gastric bypass. Anthropometric and biochemical parameters were assessed during a 1-year follow-up. Binary logistic regression analysis was used for predictors and ROC for cutoff points. There was significant reduction of medication for diabetes and hypertension. Overall remission of T2DM was 80.2 %. Preoperative albumin/creatinine ratio (ACR) and serum creatinine (SCr) levels could be predictors for DN remission, and the cutoff points were 126 mg/g cr and 57 μmol/L, respectively. Gastric bypass showed improvement of T2DM and DN. Gastric bypass may be more beneficial for those with lower preoperative ACR and SCr.

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References

    1. National Diabetes Research Group A mass survey of diabetes mellitus in a pospulation of 300,000 in 14 provinces and municipalities in China. Zhonghua Nei Ke Za Zhi. 1981;20(11):678–683. - PubMed
    1. Xu Y, Wang L, He J, et al. Prevalence and control of diabetes in Chinese adults. JAMA. 2013;310(9):948–959. doi: 10.1001/jama.2013.168118. - DOI - PubMed
    1. Kikkawa R, Koya D, Haneda M. Progression of diabetic nephropathy. Am J Kidney Dis. 2003;41:S19–S21. doi: 10.1053/ajkd.2003.50077. - DOI - PubMed
    1. Atkins RC, Zimmet P. Diabetic kidney disease: act now or pay later. Kidney Int. 2010;77:375–377. doi: 10.1038/ki.2009.509. - DOI - PubMed
    1. Lim AKH. Diabetic nephropathy—complications and treatment. Int J Nephrol Renovasc Dis. 2014;7:361–381. doi: 10.2147/IJNRD.S40172. - DOI - PMC - PubMed