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Comment
. 2015;14(11):1619-20.
doi: 10.1080/15384101.2015.1032650.

A PreSTIGEous use of LncRNAs to predict enhancers

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Comment

A PreSTIGEous use of LncRNAs to predict enhancers

Shino Murakami et al. Cell Cycle. 2015.
No abstract available

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Figures

Figure 1.
Figure 1.
Different approaches for the integration of genomic data to predict functional enhancers. Various types of genomic data can be integrated using computational pipelines, such as PreSTIGE, to predict functional enhancers. Vucicevic et al. used PreSTIGE in conjunction with enhancer-associated lncRNA expression to identify cell type-specific enhancers (top), while Hah et al. used a pipeline that integrates enhancer and target gene transcription with gene looping to predict functional estrogen-regulated enhancers (bottom).

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References

    1. Hah N, Kraus WL. Mol Cell Endocrinol 2014; 382:652–64; PMID:23810978; http://dx.doi.org/10.1016/j.mce.2013.06.021 - DOI - PMC - PubMed
    1. Bonasio R, Shiekhattar R. Annu Rev Genet 2014; 48:433–55; PMID:25251851; http://dx.doi.org/10.1146/annurev-genet-120213-092323 - DOI - PMC - PubMed
    1. Hah N, et al.. Genome Res 2013; 23:1210–23; PMID:23636943; http://dx.doi.org/10.1101/gr.152306.112 - DOI - PMC - PubMed
    1. Vucicevic D, et al.. Cell Cycle 2015; 14:253–60; PMID:25607649; http://dx.doi.org/10.4161/15384101.2014.977641 - DOI - PMC - PubMed
    1. Corradin O, et al.. Genome Res 2014; 24:1–13; PMID:24196873; http://dx.doi.org/10.1101/gr.164079.113 - DOI - PMC - PubMed

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