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. 2016 Mar 1;594(5):1113-25.
doi: 10.1113/JP270078. Epub 2015 Jun 10.

Sir Joseph Barcroft: one victorian physiologist's contributions to a half century of discovery

Lawrence D Longo  1
Affiliations

Sir Joseph Barcroft: one victorian physiologist's contributions to a half century of discovery

Lawrence D Longo. J Physiol. .

Abstract

During the first half of the 20th Century, Joseph Barcroft, KBE, FRS of Cambridge University became a world leader in respiratory physiology. He determined the role of neural stimulation in the oxygen consumption of several organs, established many of the factors that regulate the binding of oxygen to haemoglobin, explored the determinants of a human's acclimatization to high altitude and developed the field of fetal cardiovascular physiology. Chair of the Cambridge Department of Physiology from 1925 to 1937, he served as a consultant and member of many UK governmental committees. During World War I, he led a British research unit exploring the effects of poisonous gases on pulmonary function and related problems. In addition to his almost 300 publications, several of his monographs are considered as classics.

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Figures

Figure 1
Figure 1
Sir Joseph Barcroft.
Figure 2
Figure 2
Alta Vista Hut, Teneriffe, 1910 (Franklin, 1953).
Figure 3
Figure 3
Capanna Regina Margherita, Monte Rosa, 1911 (Franklin, 1953).
Figure 4
Figure 4
Interior of mobile laboratory, Cerro de Pasco, 1921–1922 (Franklin, 1953)
Figure 5
Figure 5
‘Glass Chamber’ at Cambridge University, 1920 (Franklin, 1953).
Figure 6
Figure 6
Joseph Barcroft measuring blood gases, 1928 (Franklin, 1953).
Figure 7
Figure 7
Joseph Barcroft lecturing, 1935 (Franklin, 1953).
See this image and copyright information in PMC

References

    1. [Anonymous] (1947). Obituary Joseph Barcroft. Lancet 1, 430–431.
    1. Adrian ED (1949). Tributes In Haemoglobin. A Symposium Based on a Conference Held at Cambridge in June 1948 in Memory of Sir Joseph Barcroft, ed. Roughton FJW. & Kendrew JC, pp. 3–4. Butterworths Scientific Publications, London.
    1. Barclay AE, Barcroft J, Barron DH & Franklin KJ (1938). X‐ray studies of the closing of the ductus arteriosus. Br J Radiol 11, 570–585.
    1. Barclay AE, Barcroft J, Barron DH & Franklin KJ (1939). A radiographic demonstration of the circulation through the heart in the adult and in the foetus, and the identification of the ductus arteriosus. Br J Radiol 12, 505–518.
    1. Barclay AE, Franklin KJ & Prichard MML (1944). The Foetal Circulation and Cardiovascular System, and the Changes they Undergo at Birth. Blackwell Scientific Publications, Ltd, Oxford.

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