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. 2013 Dec 1;29(4):171-6.
doi: 10.5152/UCD.2013.2438. eCollection 2013.

Analysis of the factors that have an effect on hypocalcemia following thyroidectomy

Doğa Kalyoncu  1 , Doğan Gönüllü  2 , Mehmet Lari Gedik  2 , Muzaffer Er  2 , Erol Kuroğlu  2 , Ayşenur A İğdem  3 , Ferda Nihat Koksoy  2
Affiliations

Analysis of the factors that have an effect on hypocalcemia following thyroidectomy

Doğa Kalyoncu et al. Ulus Cerrahi Derg. .

Abstract

Objective: The incidence of and risk factors for hypocalcemia following thyroidectomy were evaluated in this study.

Material and methods: One hundred and ninety thyroidectomy patients were evaluated retrospectively for factors that might contribute to postoperative hypocalcemia; age, hyperthyroidism, malignancy, the extent of surgery (total/near total/subtotal thyroidectomy), cervical lymph node dissection, and incidental parathyroidectomy.

Results: The rate of transient hypocalcemia/hypoparathyroidism was 19.47%, with a permanent hypoparathyroidism rate of 4.74%. Factors affecting the development of transient hypocalcemia were found as being operated for hyperthyroidism, and use of total thyroidectomy as the surgical method. Total thyroidectomy increased the risk of postoperative hypocalcemia by 3.16 fold. Patients undergoing operations for hyperthyroidism had a 2.3 fold increase, and those undergoing total thyroidectomy had a 3.16 fold risk of postoperative hypocalcemia.

Conclusion: Hyperthyroidism surgery and total thyroidectomy lead to a higher risk of developing early postoperative or transient hypocalcemia. According to our results, no significant relationship could be established between any of the study parameters and persistent hypocalcemia.

Keywords: Thyroidectomy; permanent hypoparathyroidism; risk factors; transient hypocalcemia.

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Figures

Figure 1.
Figure 1.
Comparison of serum calcium and thyroid hormone status
Figure 2.
Figure 2.
Comparison of serum calcium and surgical technique
See this image and copyright information in PMC

References

    1. Bender Ö, Yüney E, Çapar H, Höbek A, Ağca B, Akat O, et al. Our total thyroidectomy experience. Endokrin Diyalog. 2004;1:15–18.
    1. Sadler GP, Clark OH, Van Heerden JA, Farley . Thyroid and Parathyroid. In: Schwartz SI, editor. Principles of Surgery. 7th Ed. New York: Mc Graw Hill; 1999. pp. 1661–1713.
    1. Zambudio AR, Rodríguez J, Riquelme J, Soria T, Canteras M, Parrilla P. Prospective study of postoperative complications after total thyroidectomy for multinodular goiters by surgeons with experience in endocrine surgery. Ann Surg. 2004;240:18–25. http://dx.doi.org/10.1097/01.sla.0000129357.58265.3c. - DOI - PMC - PubMed
    1. Usman A, Sayek İ. Parathyroids and its diaseases. In: Sayek İ, editor. Temel Cerrahi. 2. baskı. Ankara: Güneş Kitabevi; 1996. pp. 1584–1605.
    1. Attie JN, Khafıf RA. Preservation of parathyroid glands during total thyroidectomy: improved technique utilizing microsurgery. Am J Surg. 1975;130:399–404. http://dx.doi.org/10.1016/0002-9610(75)90472-9. - DOI - PubMed

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