Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Oct 20;31(1):20-5.
doi: 10.5152/UCD.2014.2705. eCollection 2015.

Risk factors influencing morbidity and mortality in perforated peptic ulcer disease

İlhan Taş  1 , Burak Veli Ülger  2 , Akın Önder  2 , Murat Kapan  2 , Zübeyir Bozdağ  2
Affiliations

Risk factors influencing morbidity and mortality in perforated peptic ulcer disease

İlhan Taş et al. Ulus Cerrahi Derg. .

Abstract

Objective: Peptic ulcer perforation continues to be a major surgical problem. In this study, risk factors that influence morbidity and mortality in perforated peptic ulcer disease were examined.

Material and methods: Files of 148 patients who were included in the study due to peptic ulcer perforation between January 2006 and December 2010 were retrospectively analyzed. Data regarding age, gender, complaints, time elapsed between onset of symptoms and hospital admission, physical examination findings, co-morbid diseases, laboratory and imaging findings, length of hospital stay, morbidity and mortality were recorded.

Results: The study group included 129 (87.2%) male and 19 (12.8%) female patients. The mean age was 51.7±20 (15-88) years. Forty five patients (30.4%) had at least one co-morbid disease. In the postoperative period, 30 patients (20.3%) had complications. The most common complication was wound infection. Mortality was observed in 27 patients (18.2%). The most common cause of mortality was sepsis. Multivariate analysis revealed age over 60 years, presence of co-morbidities and Mannheim peritonitis index as independent risk factors for morbidity. Age over 60 years, time to admission and Mannheim peritonitis index were detected as independent risk factors for mortality.

Conclusion: Early diagnosis and proper treatment are important in patients presenting with peptic ulcer perforation.

Keywords: Peptic ulcer perforation; morbidity; mortality; risk factors; time to admission.

PubMed Disclaimer

References

    1. Sayek İ, Abbasoğlu O. In: Temel Cerrahi. 2nd ed. Sayek İ, editor. Güneş Kitapevi; Ankara: 1996. Peptik ülser; pp. 1031–1046.
    1. Cuschieri A. Laparoscopic vagotomy: Gimmick or reality? Surg Clin North Am. 1992;72:357–367. - PubMed
    1. Druart ML, Van Hee R, Etienne J, Cadirere GB, Gigot JF, Legrant M. Laparoscopic repair of perforated duodenal ulcer. A prospective multicenter clinical trial. Surg Endosc. 1997;11:1017–1020. - PubMed
    1. Mutter D, Evrard S, Keller P, Vix M, Vartolomei S, Marescaux J. Treatment of perforated duodenal ulcer: the celioscopic approach. Ann Chir. 1994;48:339–344. - PubMed
    1. Chalstrey LJ. (Çev: Andican A): Peptik ülser perforasyonları. In: Schwartz SI, Ellis H, editors. (Çev- Ed: Andican A), in Maingot Abdominal Operasyonlar. Nobel Tıp Kitapevi; İstanbul: 1989. pp. 639–655.

LinkOut - more resources