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. 2014 Dec 9:19:359.
doi: 10.11604/pamj.2014.19.359.2322. eCollection 2014.

The prevalence and plasmid profile of non-typhoidal salmonellosis in children in Lagos metropolis, South-western Nigeria

Ajoke Olutola Adagbada  1 , Akitoye Olusegun Coker  1 , Stella Ifeanyi Smith  2 , Solayide Abosede Adesida  3
Affiliations

The prevalence and plasmid profile of non-typhoidal salmonellosis in children in Lagos metropolis, South-western Nigeria

Ajoke Olutola Adagbada et al. Pan Afr Med J. .

Abstract

Introduction: Non-typhoidal Salmonella is the causative agent of gastroenteritis, a food-borne and zoonotic infection which is a major cause of high morbidity and death among children under 5 years of age especially from resource poor settings like the developing countries.

Methods: This study was carried out for 6 months to determine the prevalence and plasmid profile of non-typhoidal salmonellosis in children in Lagos metropolis. A total of 105 stool samples were collected from diarrheal children aged 3 months to 12 years and processed during this period. The isolates were identified using Selenite F Broth, Salmonella-Shigella Agar, Kligler Iron Agar, and Motility-indole-Urea medium, citrate and sugar utilization tests.

Results: A total number of 127 isolates were identified, 2 of which are Salmonella enteritidis (1.6%). The non-typhoidal Salmonellae were sensitive to ciprofloxacin, cetotaxime, streptomycin, cotrimxazole and tetracycline. Only one of the 2 isolates (50%) was sensitive to amoxillin and sulphonamide while none of them (0%) was sensitive to cefuroxime.

Conclusion: The plasmid analysis of the isolates showed that they harboured no detectable plasmids; this suggests that the resistance was chromosomally mediated.

Keywords: Prevalence; children; plasmid; salmonellosis.

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Figures

Figure 1
Figure 1
Agarose gel electrophoresis showing plasmid profile of Salmonella enteritidis
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References

    1. Majowicz SE, Musto J, Scallan E. The International Collaboration on Enteric Disease “Burden of Illness” studies: the global burden of nontyphoidal Salmonella gastroenteritis. Clin Infect Dis. 2010;50(6):882–889. - PubMed
    1. Jawetz Melnick, Adelberg . Medical Microbiology. 23rd ed. 2004. Salmonella-Arizona group; pp. 257–260.
    1. Centers for Disease Control (CDC) Preliminary FoodNet data on the incidence of infection with pathogens transmitted commonly through food-10 states, United States. Morbid Mortal Wkly Rep. 2008;57:366–370. - PubMed
    1. Cianflone NFC. Salmonellosis and the GI Tract: More than Just Peanut Butter. Curr Gastroenterol Rep. 2008;10(4):424–431. - PMC - PubMed
    1. Jacobson ER. Boca Raton FL: CRC/Taylor & Francis; 2007. Infectious diseases and pathology of reptiles.