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. 2015:11:64-67.
doi: 10.1016/j.ijscr.2015.04.014. Epub 2015 Apr 9.

A rare submucosal tumour of stomach-glomus tumour: A case report

Madhusudhanan Devanathan  1 , S Jamuna Rani  2 , S M Chandramohan  3 , Sasivannan Anbarasu  4
Affiliations

A rare submucosal tumour of stomach-glomus tumour: A case report

Madhusudhanan Devanathan et al. Int J Surg Case Rep. 2015.

Abstract

Introduction: Glomus tumour (GT) of the stomach is a rare submucosal mesenchymal tumour. Gastric glomus tumours are clinically recognized as benign. Nevertheless, some show biological behaviour similar to that of malignant lesions and presurgical confirmation is often impossible.

Presentation of case: A 32 year old female who presented with epigastric pain and was subsequently investigated for a antral tumour of the stomach and Wedge resection of tumour was done. Immunohistochemistry demonstrated strong positivity of smooth muscle actin and vimentin with low rate of mitosis studied by ki-67.

Discussion: We discuss the preoperative investigation, the diagnostic problems and the surgical treatment of the patient with gastric glomus tumour.

Conclusion: Glomus tumours should be considered as differential diagnosis for submucosal tumours of stomach.

Keywords: Glomus tumour; Immunohistochemistry; Stomach; Submucosal mesenchymal tumour; Wedge resection.

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Figures

Fig. 1
Fig. 1
Polypoidal mass on endoscopy along greater curvature.
Fig. 2
Fig. 2
CECT abdomen showing a lobulated mass protruding into the lumen.
Fig. 3
Fig. 3
(a) antral mass along greater curvature (b) wedge resection of mass with staplers (c) resected specimen confirming the submucosal location.
Fig. 4
Fig. 4
(a) H&E showing solid sheets of tumour cells intervined by blood vessels of varying size (10X) (b) High Power showing cuffs of tumour cells around the blood vessels lined by flattened endothelial cells (40X).
See this image and copyright information in PMC

References

    1. Wang Z.-B., Yuan J., Shi H.-Y. Features of gastric glomus tumour: a clinicopathologic, immunohistochemical and molecular retrospective study. Int. J. Clin. Exp. Pathol. 2014;4:1438–1448. - PMC - PubMed
    1. Thambi R., Sheeja S., Joesph C.P., Poothiode U. Gastric glomus tumour: a brief report. Indian J. Pathol. Micobiol. 2014;57(July–September (3)):509–510. - PubMed
    1. Vassiliou I., Tympa A., Theodosopoulos T., Dafnios N., Fragulidis G., Koureas A., Kairi E. Gastric glomus tumour: a case report. World J. Surg. Oncol. 2010;8(19):1–5. - PMC - PubMed
    1. Nascimento E.F.R., Fonte F., Mendonça R.L., Nonose R., de Souza C.A.F., Martinez C.A. Glomus Tumour of the stomach: a rare cause of upper gastrointestinal bleeding. Case Rep. Surg. 2011;2011:1–5. - PMC - PubMed
    1. Sato T., Peiper M., Fritscher-Ravens A., Gocht A., Soehendra N., Knoefel W.T. Strategy of treatment of submucosal gastric tumours. Eur. J. Med. Res. 2005;10:292–295. - PubMed