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Review
. 2015 May 7;161(4):710-3.
doi: 10.1016/j.cell.2015.04.021. Epub 2015 Apr 30.

An Adenine Code for DNA: A Second Life for N6-Methyladenine

Holger Heyn  1 , Manel Esteller  2
Affiliations
Free article
Review

An Adenine Code for DNA: A Second Life for N6-Methyladenine

Holger Heyn et al. Cell. .
Free article

Abstract

DNA N6-methyladenine (6mA) protects against restriction enzymes in bacteria. However, isolated reports have suggested additional activities and its presence in other organisms, such as unicellular eukaryotes. New data now find that 6mA may have a gene regulatory function in green alga, worm, and fly, suggesting m6A as a potential "epigenetic" mark.

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