The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository

Terry L Jernigan¹, Timothy T Brown², Donald J Hagler Jr³, Natacha Akshoomoff⁴, Hauke Bartsch⁵, Erik Newman⁴, Wesley K Thompson⁶, Cinnamon S Bloss⁷, Sarah S Murray⁸, Nicholas Schork⁹, David N Kennedy¹⁰, Joshua M Kuperman³, Connor McCabe¹¹, Yoonho Chung¹², Ondrej Libiger⁷, Melanie Maddox¹³, B J Casey¹⁴, Linda Chang¹⁵, Thomas M Ernst¹⁵, Jean A Frazier¹⁰, Jeffrey R Gruen¹⁶, Elizabeth R Sowell¹⁷, Tal Kenet¹⁸, Walter E Kaufmann¹⁹, Stewart Mostofsky²⁰, David G Amaral²¹, Anders M Dale²²; Pediatric Imaging, Neurocognition and Genetics Study

Affiliations

¹ Center for Human Development, University of California, San Diego, La Jolla, CA, USA; Department of Cognitive Science, University of California, San Diego, La Jolla, CA, USA; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA. Electronic address: tjernigan@ucsd.edu.
² Multimodal Imaging Laboratory, University of California, San Diego, La Jolla, CA, USA; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
³ Multimodal Imaging Laboratory, University of California, San Diego, La Jolla, CA, USA; Department of Radiology, University of California, San Diego, La Jolla, CA, USA.
⁴ Center for Human Development, University of California, San Diego, La Jolla, CA, USA; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
⁵ Multimodal Imaging Laboratory, University of California, San Diego, La Jolla, CA, USA.
⁶ Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA; Stein Institute for Research on Aging, University of California, San Diego, La Jolla, CA, USA.
⁷ The Qualcomm Institute, University of California, San Diego, La Jolla, CA, USA.
⁸ Department of Pathology, University of California, San Diego, La Jolla, CA, USA.
⁹ Human Biology, J. Craig Venter Institute, USA.
¹⁰ Department of Psychiatry, University of Massachusetts Medical School, Boston, MA, USA.
¹¹ Department of Psychology, University of Washington, Seattle, WA, USA.
¹² Department of Psychology, Yale University, New Haven, CT, USA.
¹³ Center for Human Development, University of California, San Diego, La Jolla, CA, USA.
¹⁴ Sackler Institute for Developmental Psychobiology, Weil Cornell Medical College, New York, NY, USA.
¹⁵ Department of Medicine, University of Hawaii, Queen's Medical Center, Honolulu, HI, USA.
¹⁶ Departments of Pediatrics and Genetics, Yale University, School of Medicine, New Haven, CT, USA.
¹⁷ Department of Pediatrics, University of Southern California, Children's Hospital Los Angeles, Los Angeles, CA, USA.
¹⁸ Department of Neurology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA.
¹⁹ Boston Children's Hospital, Boston, MA, USA.
²⁰ Kennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
²¹ Department of Psychiatry and Behavioral Sciences, University of California-Davis, Davis, CA, USA.
²² Department of Cognitive Science, University of California, San Diego, La Jolla, CA, USA; Multimodal Imaging Laboratory, University of California, San Diego, La Jolla, CA, USA; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA; Department of Radiology, University of California, San Diego, La Jolla, CA, USA.

PMID: 25937488
PMCID: PMC4628902
DOI: 10.1016/j.neuroimage.2015.04.057

The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository

Terry L Jernigan et al. Neuroimage. 2016.

. 2016 Jan 1;124(Pt B):1149-1154.

doi: 10.1016/j.neuroimage.2015.04.057. Epub 2015 May 1.

Authors

Affiliations

¹ Center for Human Development, University of California, San Diego, La Jolla, CA, USA; Department of Cognitive Science, University of California, San Diego, La Jolla, CA, USA; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA. Electronic address: tjernigan@ucsd.edu.
² Multimodal Imaging Laboratory, University of California, San Diego, La Jolla, CA, USA; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
³ Multimodal Imaging Laboratory, University of California, San Diego, La Jolla, CA, USA; Department of Radiology, University of California, San Diego, La Jolla, CA, USA.
⁴ Center for Human Development, University of California, San Diego, La Jolla, CA, USA; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA.
⁵ Multimodal Imaging Laboratory, University of California, San Diego, La Jolla, CA, USA.
⁶ Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA; Stein Institute for Research on Aging, University of California, San Diego, La Jolla, CA, USA.
⁷ The Qualcomm Institute, University of California, San Diego, La Jolla, CA, USA.
⁸ Department of Pathology, University of California, San Diego, La Jolla, CA, USA.
⁹ Human Biology, J. Craig Venter Institute, USA.
¹⁰ Department of Psychiatry, University of Massachusetts Medical School, Boston, MA, USA.
¹¹ Department of Psychology, University of Washington, Seattle, WA, USA.
¹² Department of Psychology, Yale University, New Haven, CT, USA.
¹³ Center for Human Development, University of California, San Diego, La Jolla, CA, USA.
¹⁴ Sackler Institute for Developmental Psychobiology, Weil Cornell Medical College, New York, NY, USA.
¹⁵ Department of Medicine, University of Hawaii, Queen's Medical Center, Honolulu, HI, USA.
¹⁶ Departments of Pediatrics and Genetics, Yale University, School of Medicine, New Haven, CT, USA.
¹⁷ Department of Pediatrics, University of Southern California, Children's Hospital Los Angeles, Los Angeles, CA, USA.
¹⁸ Department of Neurology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA.
¹⁹ Boston Children's Hospital, Boston, MA, USA.
²⁰ Kennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
²¹ Department of Psychiatry and Behavioral Sciences, University of California-Davis, Davis, CA, USA.
²² Department of Cognitive Science, University of California, San Diego, La Jolla, CA, USA; Multimodal Imaging Laboratory, University of California, San Diego, La Jolla, CA, USA; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA; Department of Radiology, University of California, San Diego, La Jolla, CA, USA.

PMID: 25937488
PMCID: PMC4628902
DOI: 10.1016/j.neuroimage.2015.04.057

Abstract

The main objective of the multi-site Pediatric Imaging, Neurocognition, and Genetics (PING) study was to create a large repository of standardized measurements of behavioral and imaging phenotypes accompanied by whole genome genotyping acquired from typically-developing children varying widely in age (3 to 20 years). This cross-sectional study produced sharable data from 1493 children, and these data have been described in several publications focusing on brain and cognitive development. Researchers may gain access to these data by applying for an account on the PING portal and filing a data use agreement. Here we describe the recruiting and screening of the children and give a brief overview of the assessments performed, the imaging methods applied, the genetic data produced, and the numbers of cases for whom different data types are available. We also cite sources of more detailed information about the methods and data. Finally we describe the procedures for accessing the data and for using the PING data exploration portal.

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The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository

Affiliations

The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository

Authors

Affiliations

Abstract

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