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Review
. 2015 May;33(2):169-79.
doi: 10.1016/j.ccl.2015.01.001.

Familial hypercholesterolemia

Victoria Enchia Bouhairie  1 , Anne Carol Goldberg  2
Affiliations
Review

Familial hypercholesterolemia

Victoria Enchia Bouhairie et al. Cardiol Clin. 2015 May.

Abstract

Familial hypercholesterolemia is a common, inherited disorder of cholesterol metabolism that leads to early cardiovascular morbidity and mortality. It is underdiagnosed and undertreated. Statins, ezetimibe, bile acid sequestrants, niacin, lomitapide, mipomersen, and low-density lipoprotein (LDL) apheresis are treatments that can lower LDL cholesterol levels. Early treatment can lead to substantial reduction of cardiovascular events and death in patients with familial hypercholesterolemia. It is important to increase awareness of this disorder in physicians and patients to reduce the burden of this disorder.

Keywords: Bile acid sequestrants; Ezetimibe; Familial hypercholesterolemia; LDL apheresis; Lomitapide; Mipomersen; Statins.

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Conflict of interest statement

Conflict of interest Statement: Victoria Bouhairie, MD: none

Republished in

  • Familial Hypercholesterolemia.
    Bouhairie VE, Goldberg AC. Bouhairie VE, et al. Endocrinol Metab Clin North Am. 2016 Mar;45(1):1-16. doi: 10.1016/j.ecl.2015.09.001. Endocrinol Metab Clin North Am. 2016. PMID: 26892994 Review.

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