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Case Reports
. 2015 Jan-Mar;32(1):59-61.
doi: 10.4103/0970-9371.155241.

Polymorphous low grade adenocarcinoma of lip clinically mimicking squamous cell carcinoma: An unusual presentation

Reena Tomar  1 , Neeraj Garg  1 , Sarla Agarwal  1
Affiliations
Case Reports

Polymorphous low grade adenocarcinoma of lip clinically mimicking squamous cell carcinoma: An unusual presentation

Reena Tomar et al. J Cytol. 2015 Jan-Mar.

Abstract

Polymorphous low grade adenocarcinoma (PLGA) is a malignant neoplasm that frequently occurs in the minor salivary glands in palate and oral cavity. We present a case of upper lip swelling with ulceroproliferative growth, clinically mimicking squamous cell carcinoma (SCC). Fine-needle aspiration cytology smears suggested PLGA, which was later confirmed on histopathology. Clinical presentation of PLGA may simulate SCC.

Keywords: Minor salivary gland neoplasm; polymorphous low grade adenocarcinoma; squamous cell carcinoma; upper lip.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
(a-c) Giemsa and Papanicolaou smears are highly cellular showing cells arranged in flat sheets and pseudopapillary pattern in myxoid background. Cells are cuboidal to columnar with uniform, round or oval nuclei and moderate amount of cytoplasm and inconspicuous nucleoli. Hyaline stromal globules seen occasionally. There was no necrosis and mitosis (a,b: Giemsa, ×200; c: Pap, ×200). (d) Histopathology sections showed tubular, cribriform, papillary and tubulopapillary patterns which were cystically dilated and lined by cuboidal epithelium and filled with eosinophilic secretions in the lumen with scant stroma (H and E, ×100)
See this image and copyright information in PMC

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