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Review
. 2015 May-Jun;20(3):155-60.
doi: 10.1016/j.rpor.2015.01.007. Epub 2015 Mar 6.

Breast cancer in young women in southern Tunisia: Anatomical study and clinical prognostic factors: About a series of 83 patients

Mouna Kallel  1 , Fatma Elloumi  1 , Abdelmajid Khabir  2 , Lilia Ghorbal  1 , Souhir Chaabouni  1 , Habib Amouri  3 , Mounir Frikha  2 , Jamel Daoud  4
Affiliations
Review

Breast cancer in young women in southern Tunisia: Anatomical study and clinical prognostic factors: About a series of 83 patients

Mouna Kallel et al. Rep Pract Oncol Radiother. 2015 May-Jun.

Abstract

Purpose: To define epidemiological, clinical, therapeutic and prognostic factors influencing survival of breast cancer in young women younger than 35 in southern Tunisia.

Material and methods: This is a retrospective study of 83 patients younger than 35 years and treated within tumors mammary committee of Sfax.

Results: The mean age was 31.7 years. T2 stage, high grade with positive node tumors were frequent. Breast surgery was performed for 73 patients. Chemotherapy was neo-adjuvant, adjuvant and palliative for respectively 10, 62 and 13 patients. Radiotherapy was delivered for 65 patients with curative intent and for 8 metastatic patients. Endocrine therapy was adjuvant in 38 patients and palliative in 6 cases. The overall survival (OS) at 5 years was 66.8%. Pejorative prognostic factors in uni-variate analysis were clinical T stage (T3, T4), and the number of involved lymph nodes.

Conclusion: Despite adequate treatment, the prognosis of breast cancer in young women remains worse. Early diagnosis is necessary to promote outcome.

Keywords: Breast; Cancer; Clinical; Prognosis; Young women.

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Figures

Fig. 1
Fig. 1
T clinical distribution.
Fig. 2
Fig. 2
Kaplain Meyer estimates of OS by number of involved lymph nodes.
Fig. 3
Fig. 3
Kaplain Meyer estimates of OS by T stage.
See this image and copyright information in PMC

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