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. 2009 Apr;2(2):111-8.
doi: 10.1093/ndtplus/sfp001. Epub 2009 Jan 30.

Pain management in patients with chronic kidney disease

Phuong-Chi T Pham  1 , Edgar Toscano  1 , Phuong-Mai T Pham  2 , Phuong-Anh T Pham  3 , Son V Pham  4 , Phuong-Thu T Pham  5
Affiliations

Pain management in patients with chronic kidney disease

Phuong-Chi T Pham et al. NDT Plus. 2009 Apr.

Abstract

Pain has been reported to be a common problem in the general population and end-stage renal disease (ESRD) patients. Although similar data for pre-ESRD patients are lacking, we recently reported that the prevalence of pain is also very high (>70%) among pre-ESRD patients at a Los Angeles County tertiary referral centre. The high prevalence of pain in the CKD population is particularly concerning because pain has been shown to be associated with poor quality of life. Of greater concern, poor quality of life, at least in dialysis patients, has been shown to be associated with poor survival. We herein discuss the pathophysiology of common pain conditions, review a commonly accepted approach to the management of pain in the general population, and discuss analgesic-induced renal complications and therapeutic issues specific for patients with reduced renal function.

Keywords: NSAIDS; analgesics; chronic kidney disease; opioids; pain.

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References

    1. Eriksen J, Jensen MK, Sjøgren P, et al. Epidemiology of chronic non-malignant pain in Denmark. Pain. 2003;106:221–228. - PubMed
    1. Rustoen T, Wahl AK, Hanestad BR, et al. Prevalence and characteristics of chronic pain in the general Norwegian population. Eur J Pain. 2004;8:555–565. - PubMed
    1. National Center of Health Statistics 2006. Special Feature: Pain. Health, United States, 2006, with Chart book on Trends in the Health of Americans. Hyattsville, MD.
    1. Murtagh FEM, Addington-Hall J, Higginson IJ. The prevalence of symptoms in end-stage renal disease: a systematic review. Adv Chronic Kid Dis. 2007;14:82–99. - PubMed
    1. Dewar K, Hashmi S, Pham PT, et al. Chronic kidney disease and pain. J Am Soc Nephrol. 2006:F-PO 226. (abstract)

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