Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Apr-Jun;4(2):193-9.
doi: 10.4103/2249-4863.154630.

Resistant hypertension: an approach to management in primary care

Julian P Yaxley  1 , Sam V Thambar  2
Affiliations

Resistant hypertension: an approach to management in primary care

Julian P Yaxley et al. J Family Med Prim Care. 2015 Apr-Jun.

Abstract

Hypertension is widely encountered in family medicine. Despite its prevalence, many patients have uncontrolled or difficult-to-control blood pressure. Resistant hypertension is defined as hypertension that is poorly responsive to treatment and requires the use of multiple medications to achieve acceptable blood pressure ranges. It may be a consequence of secondary hypertension or have no identifiable cause. Resistant hypertension is important to recognise because it places patients at risk of end-organ damage. Primary care physicians should be aware of the therapeutic approach for hypertension when traditional therapy fails. This article aims to familiarise readers with the evaluation and management of resistant hypertension by outlining the most recent evidence-based treatment options.

Keywords: Blood pressure; cardiovascular disease; renal denervation; resistant hypertension.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Stepwise pharmacologic management of resistant hypertension
See this image and copyright information in PMC

References

    1. Australian Institute of Health and Welfare. High Blood Pressure [internet] 2013. [updated 2013 Sep 18; cited 2014 Jan 14]. Available from: http://www.aihw.gov.au/high-blood-pressure .
    1. Canberra: National Heart Foundation of Australia; 2012. National Heart Foundation of Australia. High blood pressure statistics.
    1. Murtagh J. North Ryde: McGraw-Hill Australia Pty Ltd; 2011. Murtagh's General Practice.
    1. James P, Oparil S, Carter B, Cushman W, Dennison-Himmelfarb C, Handler J, et al. 2014 Evidence-based guidelines for the management of high blood pressure in adults; Report from the panel members appointed to the eighth joint national committee (JNC 8) JAMA. 2014;311:507–20. - PubMed
    1. Pimenta E, Calhoun D. Treatment of resistant hypertension. J Hypertension. 2010;28:2194–5. - PubMed