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Comment
. 2015 May 7;125(19):2877-8.
doi: 10.1182/blood-2015-03-636324.

Making a little go a long way.

Stella M Davies  1
Affiliations
Free article
Comment

Making a little go a long way.

Stella M Davies. Blood. .
Free article

Abstract

In this issue of Blood, Popat et al report the results of a clinical trial designed to test the safety and feasibility of a novel strategy, enforced fucosylation, intended to improve engraftment after donor unrelated cord blood (UCB) transplantation in adults. The data show that the strategy is safe, and that engraftment of platelets and neutrophils is faster in recipients of the modified cord blood (CB) unit when compared with historical controls

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  • Enforced fucosylation of cord blood hematopoietic cells accelerates neutrophil and platelet engraftment after transplantation.
    Popat U, Mehta RS, Rezvani K, Fox P, Kondo K, Marin D, McNiece I, Oran B, Hosing C, Olson A, Parmar S, Shah N, Andreeff M, Kebriaei P, Kaur I, Yvon E, de Lima M, Cooper LJ, Tewari P, Champlin RE, Nieto Y, Andersson BS, Alousi A, Jones RB, Qazilbash MH, Bashir Q, Ciurea S, Ahmed S, Anderlini P, Bosque D, Bollard C, Molldrem JJ, Chen J, Rondon G, Thomas M, Miller L, Wolpe S, Simmons P, Robinson S, Zweidler-McKay PA, Shpall EJ. Popat U, et al. Blood. 2015 May 7;125(19):2885-92. doi: 10.1182/blood-2015-01-607366. Epub 2015 Mar 16. Blood. 2015. PMID: 25778529 Free PMC article.