Solitary plasmacytoma of the cecum and the ascending colon: surgical resection as a treatment modality

Abstract

Colonic solitary plasmacytoma is a rare disease, with few reports occurring in the literature. Solitary plasmacytoma is defined as a plasma cell tumour with no evidence of bone marrow infiltration. Plasmacytoma can present as a solitary tumour in bone or in other parts of the body. The gastrointestinal tract is rarely the site of the disease. We report on the case of a 51-year-old man presenting with a colonic symptomatic mass with unclear biopsy results. A resected specimen showed a solitary plasmacytoma. Surgical resection was an adequate treatment modality in this case. Endoscopic resection, radiotherapy, and chemotherapy are also preferred treatments in selected gastrointestinal plasmacytoma cases.

Figure 1

Colonoscopic appearance of lesion.

Figure 2

Resected specimen.

Figure 3

Many of the plasma cells reacted with antibody to Kappa light chain (b) and were not stained with antibody to Lambda light chain except for fewer nonneoplastic plasma cells (a). The atypical plasmocytes expressed surface CD 38 (c).