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Review
. 2015 Mar;4(1):92-8.
doi: 10.1007/s13679-014-0132-9.

High-Risk Populations: The Pimas of Arizona and Mexico

Leslie O Schulz  1 , Lisa S Chaudhari  2
Affiliations
Review

High-Risk Populations: The Pimas of Arizona and Mexico

Leslie O Schulz et al. Curr Obes Rep. 2015 Mar.

Abstract

The purpose of this review is first, to broadly summarize the long-term commitment that began in 1965 to studying type 2 diabetes and obesity through the cooperation of the Pima Indians of Arizona, and second, to discuss the investigations with the Pima Indians of Mexico that started in 1991. The later studies emphasize gene-environment interactions in the pathogenesis of these metabolic disorders. Through the participation of both groups of Pimas, the researchers made key findings with regard to the epidemiology, physiology, clinical assessment and genetics of type 2 diabetes and obesity.

Keywords: Arizona; Mexico; Pima Indians; Type 2 diabetes; environment; genetics; lifestyle; obesity.

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Conflict of interest statement

Conflict of Interest: Leslie O. Schulz and Lisa S. Chaudhari declare that they have no conflict of interest.

References

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