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. 2015:2015:941081.
doi: 10.1155/2015/941081. Epub 2015 Mar 31.

Differential Effects of Endotracheal Suctioning on Gas Exchanges in Patients with Acute Respiratory Failure under Pressure-Controlled and Volume-Controlled Ventilation

Xiao-Wei Liu  1 , Yan Jin  1 , Tao Ma  1 , Bo Qu  2 , Zhi Liu  1
Affiliations

Differential Effects of Endotracheal Suctioning on Gas Exchanges in Patients with Acute Respiratory Failure under Pressure-Controlled and Volume-Controlled Ventilation

Xiao-Wei Liu et al. Biomed Res Int. 2015.

Abstract

This study was conducted to evaluate the effects of open endotracheal suctioning on gas exchange and respiratory mechanics in ARF patients under the modes of PCV or VCV. Ninety-six ARF patients were treated with open endotracheal suctioning and their variations in respiratory mechanics and gas exchange after the suctions were compared. Under PCV mode, compared with the initial level of tidal volume (V T ), ARF patients showed 30.0% and 27.8% decrease at 1 min and 10 min, respectively. Furthermore, the initial respiratory system compliance (C rs) decreased by 29.6% and 28.5% at 1 min and 10 min, respectively. Under VCV mode, compared with the initial level, 38.6% and 37.5% increase in peak airway pressure (PAP) were found at 1 min and 10 min, respectively. Under PCV mode, the initial PaO2 increased by 6.4% and 10.2% at 3 min and 10 min, respectively, while 18.9% and 30.6% increase of the initial PaO2 were observed under VCV mode. Summarily, endotracheal suctioning may impair gas exchange and decrease lung compliance in ARF patients receiving mechanical ventilation under both PCV and VCV modes, but endotracheal suctioning effects on gas exchange were more severe and longer-lasting under PCV mode than VCV.

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Figures

Figure 1
Figure 1
Changes in tidal volume (V T) under PCV mode of ARF patients before and after suctioning at different time points.
Figure 2
Figure 2
Changes in respiratory system compliance (C rs) of ARF patients before and after suctioning at different time points under PCV and VCV modes.
Figure 3
Figure 3
Changes in airway pressure of ARF patients before and after suctioning at different time points under VCV mode.
Figure 4
Figure 4
Changes in PaO2 of ARF patients before and after suctioning at different time points under PCV and VCV modes.
See this image and copyright information in PMC

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