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Comment
. 2015 May 5;108(9):2096.
doi: 10.1016/j.bpj.2015.03.057.

Of rafts and lipid chain lengths

Kalina Hristova  1 , Anne Hinderliter  2
Affiliations
Comment

Of rafts and lipid chain lengths

Kalina Hristova et al. Biophys J. .
No abstract available

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Figures

Figure 1
Figure 1
(Left) In the case of milk sphingomyelin (SM) and interdigitating chains, all fluorescent probes exhibited very similar behavior (partitioning) in the outer and inner leaflets, indicative of strong interleaf coupling. The blue regions represent liquid-ordered domains with similar physical-chemical properties from which all fluorescent probes were excluded. (Right) In the case of egg SM and no interdigitation, the coupling was weaker, with a probe exhibiting different behaviors in the two leaflets. Thus, the degree of SM chain interdigitation controlled the strength of interleaflet coupling, and, ultimately, the organization of the membrane.
See this image and copyright information in PMC

Comment on

References

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    1. Lin Q., London E. Interleaflet coupling in cholesterol-rich asymmetric vesicles induces interdigitation-enhanced ordered domains (rafts) in inner leaflets composed of lipids highly resistant to raft formation. Biophys. J. 2015;108:2212–2222. - PMC - PubMed

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