Rods Feed Cones to Keep them Alive
- PMID: 25957678
- DOI: 10.1016/j.cell.2015.04.031
Rods Feed Cones to Keep them Alive
Abstract
Cone photoreceptors, responsible for high-resolution and color vision, progressively degenerate following the death of rod photoreceptors in the blinding disease retinitis pigmentosa. Aït-Ali et al. describe a molecular mechanism by which RdCVF, a factor normally released by rods, controls glucose entry into cones, enhancing their survival.
Copyright © 2015 Elsevier Inc. All rights reserved.
Comment on
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Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis.Cell. 2015 May 7;161(4):817-32. doi: 10.1016/j.cell.2015.03.023. Cell. 2015. PMID: 25957687
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