Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 May 10:16:112.
doi: 10.1186/s12891-015-0564-8.

A scoping review of the proximal humerus fracture literature

Affiliations

A scoping review of the proximal humerus fracture literature

Gerard P Slobogean et al. BMC Musculoskelet Disord. .

Abstract

Background: Proximal humerus fractures are a common fragility fracture that significantly affects the independence of older adults. The outcomes of these fractures are frequently disappointing and previous systematic reviews are unable to guide clinical practice. Through an integrated knowledge user collaboration, we sought to map the breadth of literature available to guide the management of proximal humerus fractures.

Methods: We utilized a scoping review technique because of its novel ability to map research activity and identify knowledge gaps in fields with diverse treatments. Through multiple electronic database searches, we identified a comprehensive body of proximal humerus fracture literature that was classified into eight research themes. Meta-data from each study were abstracted and descriptive statistics were used to summarize the results.

Results: 1,051 studies met our inclusion criteria with the majority of research being performed in Europe (64%). The included literature consists primarily of surgical treatment studies (67%) and biomechanical fracture models (10%). Nearly half of all clinical studies are uncontrolled case series of a single treatment (48%). Non-randomized comparative studies represented 12% of the literature and only 3% of the studies were randomized controlled trials. Finally, studies with a primary outcome examining the effectiveness of non-operative treatment or using a prognostic study design were also uncommon (4% and 6%, respectively).

Conclusions: The current study provides a comprehensive summary of the existing proximal humerus fracture literature using a thematic framework developed by a multi-disciplinary collaboration. Several knowledge gaps have been identified and have generated a roadmap for future research priorities.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Scoping review overview.
Figure 2
Figure 2
Literature search and screening flow chart.
Figure 3
Figure 3
Location of research.
Figure 4
Figure 4
Cumulative number of publications by five year Increments and theme.
Figure 5
Figure 5
Proportion of proximal humerus fracture literature by theme.

References

    1. Osteoporosis Canada. Facts and Statistics. Available at: http://www.osteoporosis.ca/osteoporosis-and-you/osteoporosis-facts-and-s.... Accessed March 27, 2012.
    1. Tarride JE, Hopkins RB, Leslie WD, Morin S, Adachi JD, Papaioannou A, et al. The burden of illness of osteoporosis in Canada. Osteoporos Int. 2012;23:2591–600. doi: 10.1007/s00198-012-1931-z. - DOI - PMC - PubMed
    1. Court-Brown CM, Garg A, McQueen MM. The epidemiology of proximal humeral fractures. Acta Orthop Scand. 2001;72:365–71. doi: 10.1080/000164701753542023. - DOI - PubMed
    1. Hajcsar EE, Hawker G, Bogoch ER. Investigation and treatment of osteoporosis in patients with fragility fractures. CMAJ. 2000;163:819–22. - PMC - PubMed
    1. Kim SH, Szabo RM, Marder RA. Epidemiology of humerus fractures in the United States nationwide emergency department sample, 2008. Arthritis Care Res. 2012;64:407–14. doi: 10.1002/acr.21563. - DOI - PubMed

Publication types