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Review
. 2015 Feb;10(1):44-9.
doi: 10.1159/000369845.

Tumor Bed Boost Integration during Whole Breast Radiotherapy: A Review of the Current Evidence

Pierfrancesco Franco  1 , Domenico Cante  2 , Piera Sciacero  2 , Giuseppe Girelli  2 , Maria Rosa La Porta  2 , Umberto Ricardi  1
Affiliations
Review

Tumor Bed Boost Integration during Whole Breast Radiotherapy: A Review of the Current Evidence

Pierfrancesco Franco et al. Breast Care (Basel). 2015 Feb.

Abstract

Radiation therapy delivered with hypofractionation, which involves the delivery of a higher dose per fraction in fewer fractions (generally with a lower total nominal dose) over a shorter overall treatment time, is an established therapeutic option at least for a selected group of early breast cancer patients after breast-conserving surgery. Optimal delivery of the tumor bed boost dose in terms of timing, fractionation, and total dose whenever a hypofractionated schedule is employed has yet to be established. We herein present a review of the current evidence on the role of boost integration in whole breast radiotherapy.

Keywords: Adjuvant whole breast radiotherapy; Breast cancer; Concomitant boost; Hypofractionation; IGRT; IMRT; Simultaneous integrated boost.

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Figures

Fig. 1
Fig. 1
Examples of hypofractionation and simultaneous integrated boost (SIB) delivered with static ports of tomotherapy (a right- and b left-sided breast cancer).
See this image and copyright information in PMC

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