Underestimation of the True Specificity of the Urine Lipoarabinomannan Point-of-Care Diagnostic Assay for HIV-Associated Tuberculosis

Affiliations

¹ *Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom †The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa ‡George Washington University School of Medicine and Health Sciences, Washington, DC §Department of Global Health, Academic Medical Center, Amsterdam Institute for Global Health and Development, University of Amsterdam, Amsterdam, the Netherlands ‖Division of Medical Microbiology and Institute for Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa ¶National Health Laboratory Service, Groote Schuur Hospital, Cape Town, South Africa #Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa **Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa ††Department of Medicine, Imperial College, London, United Kingdom.

Comment

Stephen D Lawn et al. J Acquir Immune Defic Syndr. 2015.

. 2015 Aug 1;69(4):e144-6.

doi: 10.1097/QAI.0000000000000672.

¹ *Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom †The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa ‡George Washington University School of Medicine and Health Sciences, Washington, DC §Department of Global Health, Academic Medical Center, Amsterdam Institute for Global Health and Development, University of Amsterdam, Amsterdam, the Netherlands ‖Division of Medical Microbiology and Institute for Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa ¶National Health Laboratory Service, Groote Schuur Hospital, Cape Town, South Africa #Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa **Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa ††Department of Medicine, Imperial College, London, United Kingdom.

No abstract available

Comment on

Value of urine lipoarabinomannan grade and second test for optimizing clinic-based screening for HIV-associated pulmonary tuberculosis.
Drain PK, Losina E, Coleman SM, Giddy J, Ross D, Katz JN, Bassett IV. Drain PK, et al. J Acquir Immune Defic Syndr. 2015 Mar 1;68(3):274-80. doi: 10.1097/QAI.0000000000000436. J Acquir Immune Defic Syndr. 2015. PMID: 25415288 Free PMC article.

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