Comparison of amine fluoride and chlorhexidine mouth rinses in the control of plaque and gingivitis--a randomized controlled clinical trial

Abstract

Objectives: The objective of this triple blind randomized controlled clinical trial was to compare the efficacy of a mouth rinse containing amine fluoride (AmF) and chlorhexidine in controlling the supragingival plaque accumulation and gingival inflammation during a 4-week period in patients with chronic gingivitis.

Subjects and methods: A total of 30 patients were participated in this study. Fifteen patients were prescribed an AmF-containing mouth rinse and 15 were prescribed a chlorhexidine mouth rinse. Plaque index, gingival index, bleeding index, tooth stain, and tongue stain (TS) were recorded at baseline, 15 days and 1-month. Patients' perception of odor, taste and any discomfort were recorded.

Results: The comparisons between the groups were done using Mann-Whitney U-test. The comparison within the group at different time visits were done using Wilcoxon signed rank test. Both the mouth rinses resulted in a significant decrease in plaque index, gingival index, bleeding index. However, AmF mouth rinse resulted in a statistically significant decrease in bleeding index and gingival index compared to chlorhexidine group. There was no significant difference in tooth stain and TS in both the groups.

Conclusions: The 4 weeks use of AmF containing mouth rinse is effective in reducing the gingival inflammation and plaque.