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. 2015 Nov;40(4):521-2.
doi: 10.1007/s11239-015-1220-8.

The contribution of apixaban renal clearance to total clearance

Charles Frost  1 , Rebecca A Boyd  2
Affiliations

The contribution of apixaban renal clearance to total clearance

Charles Frost et al. J Thromb Thrombolysis. 2015 Nov.
No abstract available

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References

    1. Kreutz R. A clinical and pharmacologic assessment of once-daily versus twice-daily dosing for rivaroxaban. J Thromb Thrombolysis. 2014;38:137–149. doi: 10.1007/s11239-013-1029-2. - DOI - PubMed
    1. Squibb B-M, Pfizer EEIG (2012) Eliquis® (apixaban) summary of product characteristics. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR__Product_Infor.... Accessed 30 Apr 2013
    1. Raghavan N, Frost CE, Yu Z, et al. Apixaban metabolism and pharmacokinetics after oral administration to humans. Drug Metab Dispos. 2009;37:74–81. doi: 10.1124/dmd.108.023143. - DOI - PubMed
    1. Frost C, Yu Z, Nepal S et al (2008) Apixaban, a direct factor Xa inhibitor: single-dose pharmacokinetics and pharmacodynamics of an intravenous formulation. J Clin Pharmacol 48:1132. Abstract 142
    1. Vakkalagadda B, Frost C, Wang J et al (2009) Effect of rifampin on the pharmacokinetics of apixaban, an oral direct inhibitor of factor Xa. J Clin Pharmacol 49:1124. Abstract 143

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